Chondroma

Chondroma is a benign tumor formed by mature, lobularly arranged cartilaginous tissue, it occurs in the 2nd − 5th decade. Microscopically, it consists of well-differentiated tissue similar to hyaline cartilage, nodularly arranged. We divide it into:

enchondroma – grows inside the bone, most often phalanges of the hands and feet;
juxtacortical chondroma – grows on the surface of the bone.

The multiple occurrence of chondromas even in long bones is called Ollier's disease (risk of malignancy).

Zvláštním nádorem z chrupavčité tkáně je chondrohamartom. Vzniká typicky subpleurálně v plicích z odštěpených kmenových buněk nezapojených do okolní tkáně (hamarcie). Mikroskopicky jej tvoří dobře diferencovaná chrupavčitá tkáň s komůrkovými buňkami, na periferii je příměs dalších tkání (respirační epitel, hladká svalovina, tuková tkáň). Nádor je řazen mezi benigní, avšak s určitým rizikem malignizace.

A special tumor of cartilaginous tissue is chondrohamartoma. It typically originates subpleurally in the lungs from cleaved stem cells not involved in the surrounding tissue (hamarcia). Microscopically, it consists of well-differentiated cartilaginous tissue with compartment cells, at the periphery there is an admixture of other tissues (respiratory epithelium, smooth muscle, adipose tissue). The tumor is classified as benign, but with a certain risk of malignancy.