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		<title>WikiLectures  - Recent changes [en]</title>
		<link>https://www.wikilectures.eu/w/Special:RecentChanges</link>
		<description>Track the most recent changes to the wiki in this feed.</description>
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		<lastBuildDate>Sun, 28 Jun 2026 09:21:49 GMT</lastBuildDate>
		<item>
			<title>Курсы йони массажа</title>
			<link>https://www.wikilectures.eu/index.php?title=%D0%9A%D1%83%D1%80%D1%81%D1%8B_%D0%B9%D0%BE%D0%BD%D0%B8_%D0%BC%D0%B0%D1%81%D1%81%D0%B0%D0%B6%D0%B0&amp;diff=98631&amp;oldid=0</link>
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			<description>&lt;p&gt;Created page with &amp;quot;Салют,&amp;lt;br&amp;gt;Друзья.&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Сегодня я бы хотел оповестить немного про как делать массаж девушке&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Я думаю Вы думаете именно про курсы сквирта или возможно желаете найти больше про курсы йони массажа?!&amp;lt;br&amp;gt;Значит эта оптимально актуальная информация про как делать мас...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Салют,&amp;lt;br&amp;gt;Друзья.&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Сегодня я бы хотел оповестить немного про как делать массаж девушке&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Я думаю Вы думаете именно про курсы сквирта или возможно желаете найти больше про курсы йони массажа?!&amp;lt;br&amp;gt;Значит эта оптимально актуальная информация про как делать массаж девушке будет для вас наиболее полезной.&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Желаете открыть партнеру океан новых удовольствий? Уникальные специальные курсы эротического массажа дадут возможность слушателям познать секретами страстного влияния. Наши ученики изучите как технику движений, и психологию страсти, освоите считывать телесные сигналы а также контролировать внутренними потоками. Курс охватывает основы тантрических практик, применение с ароматерапией а также глубокую фокусировку на чувства. Данный формат отличный выбор для людей, желающих мечтают укрепить близость с партнером либо начать профессиональный путь в сфере оздоровительных практик. Дайте любимым гармонию тела и души. Регистрируйтесь сейчас, чтобы сделаться реальным мастером страсти и наслаждения&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;На нашем сайте малость  больше про курсы для мужчин, также информацию про обучение эротическому массажу.&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Узнай Больше - как делать массаж девушке или по ссылке https://courses-massages.ru/courses/erotic-massage-courses-for-men/&amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Наши Теги: курсы для мужчин, как делать массаж девушке, &amp;lt;br&amp;gt;&amp;lt;br&amp;gt;Удачного Дня&lt;/div&gt;</description>
			<pubDate>Sat, 27 Jun 2026 01:57:07 GMT</pubDate>
			<dc:creator>SherylVanRaalte</dc:creator>
			<comments>https://www.wikilectures.eu/w/Talk:%D0%9A%D1%83%D1%80%D1%81%D1%8B_%D0%B9%D0%BE%D0%BD%D0%B8_%D0%BC%D0%B0%D1%81%D1%81%D0%B0%D0%B6%D0%B0</comments>
		</item>
		<item>
			<title>Ionization and excitation</title>
			<link>https://www.wikilectures.eu/index.php?title=Ionization_and_excitation&amp;diff=98630&amp;oldid=0</link>
			<guid isPermaLink="false">https://www.wikilectures.eu/index.php?title=Ionization_and_excitation&amp;diff=98630&amp;oldid=0</guid>
			<description>&lt;p&gt;.&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;= Ionization and Excitation =&lt;br /&gt;
Ionization and excitation are the two fundamental processes by which radiation transfers energy to matter. They occur when electromagnetic radiation or charged particles interact with atoms and molecules.&lt;br /&gt;
&lt;br /&gt;
== Excitation ==&lt;br /&gt;
Excitation is the process in which an electron absorbs energy and moves from a lower energy level to a higher energy level without leaving the atom.&lt;br /&gt;
&lt;br /&gt;
A+E→A∗&lt;br /&gt;
&lt;br /&gt;
where:&lt;br /&gt;
&lt;br /&gt;
* A = atom in ground state&lt;br /&gt;
* A∗ = excited atom&lt;br /&gt;
&lt;br /&gt;
The atom remains electrically neutral. The excited state is unstable, and the electron returns to its original energy level by releasing energy in the form of electromagnetic radiation or heat.&lt;br /&gt;
&lt;br /&gt;
== Ionization ==&lt;br /&gt;
Ionization is the process in which sufficient energy is transferred to completely remove an electron from an atom or molecule.&lt;br /&gt;
&lt;br /&gt;
A+E→A++e−&lt;br /&gt;
&lt;br /&gt;
The result is the formation of:&lt;br /&gt;
&lt;br /&gt;
* a positive ion (A+)&lt;br /&gt;
* a free electron (e−)[[File:Ionisation.gif|thumb]]&lt;br /&gt;
&lt;br /&gt;
If the free electron possesses enough kinetic energy, it can produce further ionizations, called &amp;#039;&amp;#039;&amp;#039;secondary ionization&amp;#039;&amp;#039;&amp;#039;.&lt;br /&gt;
&lt;br /&gt;
The &amp;#039;&amp;#039;&amp;#039;ionisation energy&amp;#039;&amp;#039;&amp;#039; is the minimum energy needed to remove the electron from the atom completely&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;⇒&amp;#039;&amp;#039;&amp;#039; This shows a number of possible excited states for a hydrogen atom.&lt;br /&gt;
&lt;br /&gt;
In biological tissues, radiation interacts mainly with water molecules, which constitute most of the cell mass.&lt;br /&gt;
&lt;br /&gt;
Ionization and excitation lead to:&lt;br /&gt;
&lt;br /&gt;
* formation of free radicals&lt;br /&gt;
* chemical reactions&lt;br /&gt;
* damage to proteins, membranes, and nucleic acids&lt;br /&gt;
&lt;br /&gt;
These processes are the basis of the biological effects of ionizing radiation.&lt;/div&gt;</description>
			<pubDate>Sat, 30 May 2026 07:23:40 GMT</pubDate>
			<dc:creator>Hansel</dc:creator>
			<comments>https://www.wikilectures.eu/w/Talk:Ionization_and_excitation</comments>
		</item>
		<item>
			<title>File:Ionisation.gif</title>
			<link>https://www.wikilectures.eu/index.php?title=File:Ionisation.gif&amp;diff=98629&amp;oldid=0</link>
			<guid isPermaLink="false">https://www.wikilectures.eu/index.php?title=File:Ionisation.gif&amp;diff=98629&amp;oldid=0</guid>
			<description>&lt;p&gt;&lt;a href=&quot;/index.php?title=User:Hansel&amp;amp;action=edit&amp;amp;redlink=1&quot; class=&quot;new mw-userlink&quot; title=&quot;User:Hansel (page does not exist)&quot;&gt;&lt;bdi&gt;Hansel&lt;/bdi&gt;&lt;/a&gt; uploaded &lt;a href=&quot;/w/File:Ionisation.gif&quot; title=&quot;File:Ionisation.gif&quot;&gt;File:Ionisation.gif&lt;/a&gt;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Describes excited state of Hydrogen&lt;/div&gt;</description>
			<pubDate>Sat, 30 May 2026 07:22:20 GMT</pubDate>
			<dc:creator>Hansel</dc:creator>
			<comments>https://www.wikilectures.eu/w/File_talk:Ionisation.gif</comments>
		</item>
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			<title>Oncological treatment</title>
			<link>https://www.wikilectures.eu/index.php?title=Oncological_treatment&amp;diff=98628&amp;oldid=98627</link>
			<guid isPermaLink="false">https://www.wikilectures.eu/index.php?title=Oncological_treatment&amp;diff=98628&amp;oldid=98627</guid>
			<description>&lt;p&gt;&lt;span dir=&quot;auto&quot;&gt;&lt;span class=&quot;autocomment&quot;&gt;1. Surgery&lt;/span&gt;&lt;/span&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
				&lt;col class=&quot;diff-content&quot; /&gt;
				&lt;tr class=&quot;diff-title&quot; lang=&quot;en&quot;&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 09:16, 30 May 2026&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l19&quot;&gt;Line 19:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 19:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;These effects damage cellular components, particularly DNA.&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;These effects damage cellular components, particularly DNA.&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;CITATION: https://my.clevelandclinic.org/health/treatments/cancer-treatment&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;=== Biological Effect ===&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;=== Biological Effect ===&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;

&lt;!-- diff cache key wikidblfen:diff::1.12:old-98627:rev-98628 --&gt;
&lt;/table&gt;</description>
			<pubDate>Sat, 30 May 2026 07:16:51 GMT</pubDate>
			<dc:creator>Hansel</dc:creator>
			<comments>https://www.wikilectures.eu/w/Talk:Oncological_treatment</comments>
		</item>
		<item>
			<title>Oncological treatment</title>
			<link>https://www.wikilectures.eu/index.php?title=Oncological_treatment&amp;diff=98627&amp;oldid=0</link>
			<guid isPermaLink="false">https://www.wikilectures.eu/index.php?title=Oncological_treatment&amp;diff=98627&amp;oldid=0</guid>
			<description>&lt;p&gt;Created page with &amp;quot;Oncological treatment is the use of physical and biological methods to destroy tumor cells while minimizing damage to healthy tissues. The main biophysical principles involve the interaction of &amp;#039;&amp;#039;&amp;#039;ionizing radiation, electromagnetic energy, and particles&amp;#039;&amp;#039;&amp;#039; with biological tissues.   It targets cancer through a combination of therapies tailored to the specific type, stage, and biology of the disease.  A common treatment method is:  === 1. Surgery === This is a common and...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Oncological treatment is the use of physical and biological methods to destroy tumor cells while minimizing damage to healthy tissues. The main biophysical principles involve the interaction of &amp;#039;&amp;#039;&amp;#039;ionizing radiation, electromagnetic energy, and particles&amp;#039;&amp;#039;&amp;#039; with biological tissues. &lt;br /&gt;
&lt;br /&gt;
It targets cancer through a combination of therapies tailored to the specific type, stage, and biology of the disease.&lt;br /&gt;
&lt;br /&gt;
A common treatment method is:&lt;br /&gt;
&lt;br /&gt;
=== 1. Surgery ===&lt;br /&gt;
This is a common and one of the first way to get rid of a tumor if in a accessible location often accompanied by other methods to fully eradicate any tumor cells.&lt;br /&gt;
&lt;br /&gt;
=== 2. Radiotherapy ===&lt;br /&gt;
Radiotherapy uses &amp;#039;&amp;#039;&amp;#039;ionizing radiation&amp;#039;&amp;#039;&amp;#039; (X-rays, γ-rays, electron beams) to destroy cancer cells.&lt;br /&gt;
&lt;br /&gt;
=== Principle ===&lt;br /&gt;
Ionizing radiation transfers energy to atoms and molecules, producing:&lt;br /&gt;
&lt;br /&gt;
* ionization&lt;br /&gt;
* excitation&lt;br /&gt;
* free radicals (especially from water)&lt;br /&gt;
&lt;br /&gt;
These effects damage cellular components, particularly DNA.&lt;br /&gt;
&lt;br /&gt;
=== Biological Effect ===&lt;br /&gt;
&lt;br /&gt;
* Single-strand DNA breaks&lt;br /&gt;
* Double-strand DNA breaks&lt;br /&gt;
* Chromosomal damage&lt;br /&gt;
* Cell death or loss of reproductive capacity.&lt;br /&gt;
&lt;br /&gt;
=== 3. Chemotherapy ===&lt;br /&gt;
&lt;br /&gt;
* Although primarily pharmacological, its biophysical effect is interference with:&lt;br /&gt;
&lt;br /&gt;
* DNA replication&lt;br /&gt;
* RNA synthesis&lt;br /&gt;
* protein synthesis&lt;br /&gt;
&lt;br /&gt;
Rapidly dividing tumor cells are affected most strongly.&lt;br /&gt;
&lt;br /&gt;
=== 4. Hormone therapy ===&lt;br /&gt;
Hormone therapy blocks or reduces hormones that fuel cancer cell growth. Some cancers grow more rapidly in the presence of sex hormones, like androgens or estrogen.&lt;br /&gt;
&lt;br /&gt;
Providers treat some types of prostate cancer, breast cancer and gynecological cancers (uterine and ovarian cancers) with hormone therapy.&lt;br /&gt;
&lt;br /&gt;
=== 5. Immunotherapy ===&lt;br /&gt;
Immunotherapy helps your immune system identify and destroy cancer cells. Healthy immune systems do a good job of identifying threats, like germs, and getting rid of them. Cancer cells thrive because they can hide from your immune system, so your immune system doesn’t attack the cancer cells. Immunotherapy can keep cancer cells from escaping your body’s natural defenses.&lt;br /&gt;
&lt;br /&gt;
* Usually used in combination with other therapies.&lt;br /&gt;
&lt;br /&gt;
=== 6. Ablation therapy ===&lt;br /&gt;
Ablation therapy uses extreme hot or cold energy to kill cancer cells. Some types are called “surgery” because although there aren’t physical cuts, the methods allow providers to remove tissue with near-surgical precision. &lt;br /&gt;
&lt;br /&gt;
=== 7. Hemopoietic stem cell (bone marrow) transplant ===&lt;br /&gt;
A stem cell transplant replaces immature blood cells that are (or could become) cancerous with healthy cells. &lt;br /&gt;
&lt;br /&gt;
=== 8. Targeted therapy ===&lt;br /&gt;
Targeted therapy treatments interfere with specific processes that allow some cancer cells to thrive. Cancer cells develop and multiply because of genetic mutations (changes) in their DNA. The mutations often cause cancer cells to make abnormal proteins that spur cancer cell growth. Targeted therapy drugs home in on the specific proteins, preventing them from fueling cancer cell growth.&lt;br /&gt;
&lt;br /&gt;
=== 9. Nuclear Medicine ===&lt;br /&gt;
Radioactive isotopes are used for targeted therapy.&lt;br /&gt;
&lt;br /&gt;
Examples:&lt;br /&gt;
&lt;br /&gt;
* Radioiodine (I-131) for thyroid cancer&lt;br /&gt;
* Radionuclide therapy for metastatic tumors&lt;br /&gt;
&lt;br /&gt;
Radiation emitted directly inside the body damages tumor tissue.&lt;/div&gt;</description>
			<pubDate>Sat, 30 May 2026 07:13:34 GMT</pubDate>
			<dc:creator>Hansel</dc:creator>
			<comments>https://www.wikilectures.eu/w/Talk:Oncological_treatment</comments>
		</item>
		<item>
			<title>Neurotransmission</title>
			<link>https://www.wikilectures.eu/index.php?title=Neurotransmission&amp;diff=98626&amp;oldid=0</link>
			<guid isPermaLink="false">https://www.wikilectures.eu/index.php?title=Neurotransmission&amp;diff=98626&amp;oldid=0</guid>
			<description>&lt;p&gt;Created page with &amp;quot;Neurotransmission is the process by which information is transferred from one neuron to another through &amp;#039;&amp;#039;&amp;#039;electrical and chemical signals&amp;#039;&amp;#039;&amp;#039;.  === Step 1: An action potential arrives at the axon terminal === There are a series of steps that take place during chemical synaptic transmission.  First, an action potential propagates down the axon until it arrives at the axon terminal, depolarizing the membrane of the presynaptic terminal. This results from transient changes...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;Neurotransmission is the process by which information is transferred from one neuron to another through &amp;#039;&amp;#039;&amp;#039;electrical and chemical signals&amp;#039;&amp;#039;&amp;#039;.&lt;br /&gt;
&lt;br /&gt;
=== Step 1: An action potential arrives at the axon terminal ===&lt;br /&gt;
There are a series of steps that take place during chemical synaptic transmission.&lt;br /&gt;
&lt;br /&gt;
First, an action potential propagates down the axon until it arrives at the axon terminal, depolarizing the membrane of the presynaptic terminal. This results from transient changes in membrane permeability to different ions like Na, K and Ca.&lt;br /&gt;
&lt;br /&gt;
* Resting membrane potential ≈ &amp;#039;&amp;#039;&amp;#039;−70 mV&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
* Depolarization occurs due to opening of &amp;#039;&amp;#039;&amp;#039;voltage-gated Na⁺ channels&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
* Repolarization occurs due to opening of &amp;#039;&amp;#039;&amp;#039;K⁺ channels&amp;#039;&amp;#039;&amp;#039;&lt;br /&gt;
&lt;br /&gt;
The action potential propagates along the axon as a self-regenerating electrical signal.&lt;br /&gt;
&lt;br /&gt;
=== Step 2: Membrane depolarization from action potential causes influx of calcium ions ===&lt;br /&gt;
When the action potential reaches the presynaptic terminal:&lt;br /&gt;
&lt;br /&gt;
* Voltage-gated &amp;#039;&amp;#039;&amp;#039;Ca²⁺ channels&amp;#039;&amp;#039;&amp;#039; open&lt;br /&gt;
* Ca²⁺ enters the terminal according to its electrochemical gradient&lt;br /&gt;
* Increased intracellular Ca²⁺ triggers fusion of synaptic vesicles with the presynaptic membrane&lt;br /&gt;
&lt;br /&gt;
This process converts an &amp;#039;&amp;#039;&amp;#039;electrical signal into a chemical signal&amp;#039;&amp;#039;&amp;#039;.&lt;br /&gt;
&lt;br /&gt;
=== Step 3: Docking of synaptic vesicles at the membrane ===&lt;br /&gt;
&lt;br /&gt;
* The synaptic vesicles fuse with the presynaptic membrane using SNARE proteins (v-SNARE&amp;#039;s and t-SNARE&amp;#039;s)&lt;br /&gt;
* Neurotransmitter molecules are released via exocytosis and diffuse across the synaptic cleft. Diffusion follows &amp;#039;&amp;#039;&amp;#039;Fick&amp;#039;s law&amp;#039;&amp;#039;&amp;#039;:  where:&lt;br /&gt;
** J = diffusion flux&lt;br /&gt;
** D = diffusion coefficient&lt;br /&gt;
** dC/dx = concentration gradient &lt;br /&gt;
&lt;br /&gt;
=== Step 4: Release of neurotransmitters into the synapse ===&lt;br /&gt;
The last step of neurotransmitter release is the fusing of the cell membrane. In order to release their chemical contents into the synapse, vesicles need to fuse with the cell membrane. As the vesicular membrane merges with the interior of the neuronal membrane, the membranes fuse and the contents of the vesicle become exposed to the extracellular space. The neurotransmitters then float across the aqueous synapse, giving them the opportunity to interact with postsynaptic receptors.&lt;br /&gt;
&lt;br /&gt;
=== Step 5: Receptor Activation ===&lt;br /&gt;
Neurotransmitters bind to receptors on the postsynaptic membrane.&lt;br /&gt;
&lt;br /&gt;
This causes changes in membrane conductance:&lt;br /&gt;
&lt;br /&gt;
* Opening Na⁺ channels → depolarization (&amp;#039;&amp;#039;&amp;#039;EPSP&amp;#039;&amp;#039;&amp;#039;)&lt;br /&gt;
* Opening K⁺ or Cl⁻ channels → hyperpolarization (&amp;#039;&amp;#039;&amp;#039;IPSP&amp;#039;&amp;#039;&amp;#039;)Neurotransmission ends by:&lt;br /&gt;
&lt;br /&gt;
* enzymatic degradation (e.g., acetylcholinesterase)&lt;br /&gt;
* reuptake into the presynaptic neuron&lt;br /&gt;
* diffusion away from the synapse&lt;br /&gt;
&lt;br /&gt;
CITATION:&lt;br /&gt;
https://openbooks.lib.msu.edu/introneuroscience1/chapter/neurotransmitter-release/&lt;/div&gt;</description>
			<pubDate>Sat, 30 May 2026 06:58:49 GMT</pubDate>
			<dc:creator>78.128.191.205</dc:creator>
			<comments>https://www.wikilectures.eu/w/Talk:Neurotransmission</comments>
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