Ceruloplasmin

Ceruloplazmin is a plasma protein produced in liver, which can revesibly bind 6 atoms of copper in it's molecule mědi. Defect of this form of copper transport by ceruloplasmin causes Wilson's desease Wilsonovu chorobu. Another function of ceruloplasmin is prevention of forming dangerous hydroxyl radicals, in so called Fenton reaction Fentonovou reakcí by catalizing oxidation of Fe2+ to Fe3+. Ceruloplasmin is a significant acute fase reactant. reaktant akutní fáze. It's blood concentration physiologically rises in pregnancy.

Související články

 * Plazmatické bílkoviny
 * Reaktanty akutní fáze
 * Wilsonova choroba