Dialysis-related amyloidosis

It is a type of amyloidosis, which is mainly associated with long-term hemodialysis patients. It occurs because of accumulated β2-microglobulin protein, which cannot be excreted by damaged kidneys. Constantly increased plasma concentration is required for amyloid formation. β2-microglobulin has a high affinity for collagen therefore amyloid fibrils are formed primarily in bones, joints, periarticular tissues, and tendons (carpal tunnel syndrome).

Related articles

 * Kidney amyloid
 * Carpal tunnel syndrome
 * Hemodialysis