Antithrombotics

Antithrombotic mechanisms:

Antithrombotics are substances that reduce blood clotting.
 * 1) Anticoagulants - reduce blood clotting by affecting the production and effects of coagulation factors.
 * 2) * Direct - heparin and low molecular weight heparins - act as catalytic cofactors of antithrombin III and inhibit some serine proteases coagulation cascades.
 * 3) * Indirect - oral anticoagulants (coumarol derivatives - warfarin, pelentan) - inhibit the functions of vitamin K.
 * 4) Antiplatelet agents – prevent the formation of a thrombus by inhibiting the functions of platelets – e.g. acetylsalicylic acid.
 * 5) Thrombolytics – dissolve the formed thrombus, include fibrinolytics – e.g. streptokinase.

Related Articles

 * Hemostasis
 * Anticoagulants
 * Thrombolytics
 * Hemocoagulation