Osteoclastoma

Osteoclastoma, or a giant-cell tumor of bone (GCTOB) is a tumor derived by osteoclasts. It is radiosensitive. Has a biological nature of a semi-minimal tumor.

Occurence
Occurs mainly in the 2nd to 4th decades of life. More than half are around the knee joint. other sites – distal radius, proximal humerus, pelvis, hand bones.

Differential diagnosis
Tumor of the hyperparathyroidism. thumb|right|300 px|Photomicrographs of osteoclastoma.

Metastasis
1–3% may have lung metastases within 3 years after treatment of the primary lesion. With radiotherapy, the risk of metastases is up to 24%.

Prognosis
The five-year survival of the malignant form is 50%. Chemotherapy will not affect anything.

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 * Giant bone cell tumor (specimen)