Hyperkeratosis

Hyperkeratosis is a thickening of the stratum corneum that is often associated with the presence of an abnormal amount of keratin.

Hyperkeratosis can be further distinguished:
 * Orthokeratosis (or orthokeratotic hyperkeratosis or orthohyperkeratosis) is characterized by normal keratinocyte maturation.
 * Parakeratosis' (or parakeratotic hyperkeratosis) is characterized by pathological maturation of keratinocytes, as cell nuclei are present in their cytoplasm in the stratum corneum.

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