Cluster designation

Cluster designation (sometimes also referred to as a cluster of differentiation) is the nomenclature hybridom as, which produce highly specific antibodies against certain proteins, immunoglobulin. These proteins and glycoproteins are most commonly found on leukocytes, but also on endothelium and other cells. These are  transmembrane  proteins. They are called (not quite correctly, but commonly) as  CD characters, the cells that carry them then CD-n positive (eg CD-8 + < / sup> ).

Function
The proteins that make up the antigen for a CD antibody have a very wide range of effects and functions. These include "adhesion" molecules, components of T-lymphocytes and B-lymphocytes receptors, and many others.

Diagnostic meaning
Some CD characters are so specific to each cell type that they can be used very well to accurately search for and label cells. An overview of the most important CD characters and the types of cells that carry them:

Leukemia
Upon closer diagnosis of "leukemia", CD markers that express malignant leukocytes are monitored. This makes it possible to find out quite precisely which line and at what stage of maturation it is.

Related Articles

 * T-lymphocytes
 * B-lymphocytes
 * Non-specific immunity
 * Specific immunity