Leptin

Leptin (from the greek leptos − narrow, thin) is a hormone produced by cells of adipose tissue − adipocytes. Leptin production increases with the amount of fat in the cells. In general, a low leptin concentration signals starvation. Most obese patients have hyperleptinemia. Leptin regulates food intake and energy expenditure. Peripherally affects insuline sensitivity. Phylogenetically designed to adapt the body to long-term starvation.

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