Osteopoikilosis



Osteopoicilosis (osteopoicilia) is a very rare AD hereditary disease.

It is manifested by irregular thickenings of the bone → we find round or oval islands hyperostosis inside the cancellous Bones and the metaphysis and epiphysis.

Clinical picture

 * Usually without significant clinical manifestations;
 * the disease is mostly revealed as an accidental X-ray finding;
 * in 10% affected subcutaneous and skin nodules (dermatofibrosis lenticularis disseminata - Bloch-Sulzberg syndrome).

X-ray image

 * Irregularly demarcated sclerosis → characteristic mottled appearance of the skeleton.

Treatment

 * None (illness without subjective difficulties);
 * in adults, bone metastases must be distinguished.