TPHA

TPHA (Treponema pallidum hemagglutination) is a syphilis screening test.
 * The antigen is T. pallidum ssp. Pallidum Nichols (so-called Nichols strain) bound to chicken erythrocytes. Agglutination occurs when this antigen meets serum antibodies.
 * The sensitivity of TPHA in primary syphilis is 69-90%, in secondary syphilis 100%, and later around 97%.
 * The specificity of this test is at least 98%.

Related articles

 * Syphilis
 * Fast reagent reaction