Nutritional disorders / Questions and case reports


 * 1) A girl, 17 years old, measures 170 cm and weighs 45 kg. Her average daily intake of energy nutrients is 100 g of carbohydrates, 20 g of protein and 15 g of fat.
 * 2) * 1. What is its daily energy intake (in kcal, kJ)?
 * 3) * 2. What is the value of her basal metabolism? Use a rough estimate, i.e., BMR = 24 × weight in kg.
 * 4) Kwashiorkor manifests itself:
 * 5) * A - Growth retardation
 * 6) * B - Loss of subcutaneous fat
 * 7) * C - Hypoalbuminemia
 * 8) * D - Edema
 * 9) Which vitamins are absorbed directly in the gut?
 * 10) * A - Folic acid
 * 11) * B - Biotin
 * 12) * C - B12
 * 13) * D - E
 * 14) * E - Pantothenic acid

A 78 years old woman
She has lived in a retirement home for 2 years. In recent months, she has had difficulty walking, experienced paresthesia, and numbness in her legs. A neurologist diagnosed her with peripheral neuropathy. He suspected that she is experiencing inadequate nutrition, especially with regards to vitamin intake. He examined the concentration of transketolase in erythrocytes.

Questions:


 * 1) What causes transketolase deficiency?
 * 2) What are the symptoms of thiamine pyrophosphate deficiency?

A 68 years old man
He was on parenteral nutrition for established malnutrition. He had pernicious anemia. The attending physician ordered a blood sample to be taken to determine B12 level.

Questions:


 * 1) Was this examination necessary in the patient? (Note: This is a relatively expensive examination.)

Related articles
Other chapters from the book MASOPUST, J., PRŮŠA, R .: Pathobiochemistry of metabolic pathways
 * Marasmus
 * Kwashiorkor
 * Metabolic syndrome
 * anorexia nervosa

Source

 * MASOPUST, Jaroslav and Richard PRŮŠA. Pathobiochemistry of metabolic pathways. 1st edition. Prague: Charles University, 1999. 182 pp. 208-210.  ISBN 80-238-4589-6.