Collection of chorionic villi

Chorionic villus sampling (CVS) is an invasive method used in prenatal diagnostics. We perform between 10 and 13 gestational weeks' (before amniocentesis).

Collection of chorionic tissue (it is tissue from the trophoblast, which carries the genetic information of the original embryo) is performed with a special needle under ultrasound control, most often transabdominally, less often transcervically. The main purpose of the examination is to obtain a sample of fetal tissue for examination of karyotype or for examination of the type microarray or molecular genetic examination' with the aim of excluding in fetus in chromosomal aberrations or genetically conditioned diseases. The advantage of CVS over amniocentesis is the possibility of earlier diagnosis (for example, following a first-trimester screening developmental defects). Risk of pregnancy loss 0.5-1%.

Related Articles

 * Clinical Genetics
 * Prenatal diagnosis
 * Amniocentesis
 * Cordocentesis
 * Indication of chromosomal examination