ICD-O

The International Classification of Diseases for Oncology (ICD-O) is derived from the [ICD-O] for oncological diagnoses. The third revision of the ICD-O is currently in use. Tumors are coded in the following axes:  'The classification is expressed by a combination of a three- to four-digit alphanumeric topography code'  (eg C01.1)  'b'  a five-digit code  'XXXX / Y', where the first four digits indicate the morphological type of the tumor and the number after the slash biological behavior. The next (optional) digit (sometimes listed second after the slash in the data collection) indicates the degree of tumor differentiation. Morphological codes ( XXXX ) are always four-digit numbers between 8000 and 9989.  '
 * topography
 * morphology
 * biological behavior
 * differentiation

 'The biological behavior code (' 'Y' ') can take the following values:'   'The differentiation code has the meaning of histological grading and differentiation:'   'In the case of lymphomas and  leukemias, the gross immunophenotype is given instead of the differentiation code in the National Cancer Registry:'  The classification is derived from the ICD-10 classification. Thus, the topography / localization coding for malignant neoplasms usually corresponds to the ICD-10 code. An exception is, for example, codes that already take into account the morphological type of neoplasm in ICD-10. For example, code C43.5 Malignant melanoma is code C44.3 (Torso skin) 8720/3 (Malignant melanoma NS) in ICD-O.
 * 0 - benign tumor
 * 1 - uncertain behavior, it is not certain whether it is a benign or malignant tumor
 * 2 - tumor in situ, non-invasive
 * 3 - malignant tumor, primary
 * 6 - malignant tumor, metastatic (not used in oncology registries)
 * 9 - malignant tumor, origin cannot be determined (not used in oncology registries)
 * 1 - well differentiated
 * 2 - moderately well differentiated
 * 3 - poorly differentiated
 * 4 - undifferentiated, anaplastic
 * 9 - differentiation not specified, not specified or not applicable
 * 5 - immunoprofile corresponds to  T-lymphocytes
 * 6 - immunoprofile corresponds to  B-lymphocytes
 * 7 - immunoprofile of null cells (non-B non-T cells)
 * 8 - immunoprofile corresponds to  NK cells
 * 9 - cell type not specified, not specified or not applicable

 'Example of C24.1 encoding interpretation M-8160/32:' 
 * C24 - (malignant) neoplasm of other and unspecified parts of bile ducts
 * C24.1 - Vater papilla tumor
 * C24.1 8160 - cholangiocarcinoma Vater papilla
 * C24.1 8160/3 - (malignant) cholangiocarcinoma Vater papilla
 * C24.1 8160/32 - moderately well differentiated cholangiocarcinoma Vater papilla

Source

 * ws:MKN-O

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