Granulomatous lung processes

The term granulomatosis indicates that this group includes a disease whose basic manifestation is granuloma.



Tuberculosis
Tuberculosis (TB) are diseases caused by the Mycobacterium tuberculosis complex.

You can find more detailed information on the page Tuberculosis (pneumology)

Pneumoconiosis
It is a group of diseases, that is mostly common in proffesions with high risk of inhalation of inorganic dust. The most common are: silicosis, asbestosis, pneumoconiosis of coal mines, berylliosis.

Exogenous allergic alveolitis
Another name is hypersensitivity pneumonia or allergic pneumonitis. It is a disease that develops after repeated inhalation of organic antigens in a disposable individual. It is manifested by diffuse damage of the lung parenchyma.

You can find more detailed information on the page Exogenous allergic alveolitis

Sarcoidosis
Sarcoidosis is a multisystem disease of unknown cause. It primarily affects young and middle-aged people. It is often manifested by bilateral hilar lymphadenopathy (BHL), pulmonary infiltrates, ocular and skin lesions. The disease may not manifest at all and may be asymptomatic. The "manifest form" manifests itself in acute or chronic systemic inflammatory response syndrome with respiratory symptoms. The liver, spleen, lymph nodes, salivary glands, heart, nervous system, muscles, bones and other organs can also be affected. Diagnosis is established if radiological findings are supported by histological evidence of non-caseifying granulomas from epithelioid cells. Granulomas for known causes and local sarcoid reactions must be ruled out.

Granulomatosis with polyangiitis
The older name Wegener's granulomatosis is a chronic granulomatous necrotizing vasculitis that affects most of the lower respiratory tract and kidneys. Other organs such as the skin, joints, eyes, heart, peripheral nerves and CNS may rarely be affected.

Langerhans cell granulomatosis
Also called pulmonary histiocytosis X. This disease is characterized by bronchiolocentric granulomatous inflammation with presence of cystic formations and nodules. The clinical manifestation is mainly exertional dyspnea.

Churg-Strauss syndrome
This very rare disease, which more often affects men, is characterized by three stages. In the first phase, the disease manifests itself in allergic rhinitis with nasal polyps and bronchial asthma. In the second phase, eosinophilia occurs in the blood and tissues, there are also eosinophilic pulmonary infiltrates and pleural effusion (exudate) with a high number of eosinophils, as well as eosinophilic gastroenteritis. The third stage is the stage of systemic vasculitis with damage to individual organs.

Related articles

 * Tuberculosis (pneumology)
 * Granulocytes
 * Granuloma