Essential Cryoglobulinemia

Essential cryoglobulinemia is a rare disease of small caliber vessels.
 * It can be manifested by repeated sowings of urticaria, peripheral neuropathy and organ disabilities.
 * It is characterized by the presence of cryoglobulins type II + III, which reversibly precipitate in the cold.
 * Occurrence: in lymphoproliferative diseases, bacterial + viral infections (HCV, especially in the lower limbs).