Histology MCQs/Blood and Hematopoiesis

{Which function do have azurophilic granules in leukocytes? - Derivatives of the smooth endoplasmic reticulum - Derivatives of the cytoskeleton - Cell inclusions + Lysosomes
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{Diameter of basophilic erythroblast is: - 6 to 8 μm + 10 to 16 μm - 20 μm - 22 to 25 μm
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{Diameter of megakaryocyte is: - 5 to 20 μm - 20 to 50 μm + 50 to 150 μm - 150 to 1000 μm
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{Diameter of myeloblast is: - 1 to 5 μm - 5 to 10 μm - 10 to 15 μm + 15 to 20 μm
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{Diameter of orthochromatophilic erythroblast is: - 6 to 8 μm + 8 to 10 μm - 10 to 18 μm - 20 to 25 μm
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{Diameter of proerythroblast is: + 20 μm - 40 μm - 60 μm - 80 μm
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{What is a a differential blood count (leucogram): - Relative frequency of all formed blood elements - Absolute number of all formed blood elements + Relative frequency of white blood cells - Absolute number of white blood cells
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{What are dimensions of an average red blood cell? + Diameter 7.5 μm, maximal thickness 2.6 μm, thickness in the middle 0.8 μm - Diameter 10 μm, maximal thickness 1.6 μm, thickness in the middle 0.1 μm - Diameter 7.5 μm, maximal thickness 1.6 μm, thickness in the middle 0.8 μm - Diameter 10 μm, maximal thickness 2.6 μm, thickness in the middle 0.1 μm
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{Except one, all below mentioned cells are differentiated monocytes. Which of them is the exception? - Microglia - Osteoclast + Goblet cell - Kupfer's cell
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{How is called first morphologically distinguishable stage of development of red blood cells? - Polychromatophilic erythroblast - Ortochromatophilic erythroblast - Basophilic erythroblast + Proerythroblast
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{How many of basophils are in the blood? + 0 to 1 % of all WBC's - 3 to 5 % of all WBC's - 20 to 30 % of all WBC's - 60 to 70 % of all WBC's
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{How many of eosinophils are in the blood? - 0 to 1 % of all WBC's + 2 to 5 % of all WBC's - 20 to 30 % of all WBC's - 60 to 70 % of all WBC's
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{How many of lymphocytes are in the blood? - 3 to 5 % of all WBC's - 5 to 20 % of all WBC's + 20 to 40 % of all WBC's - 60 to 70 % of all WBC's
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{How many of monocytes are in the blood? - 1 to 3 % of all WBC's + 2 to 10 % of all WBC's - 20 to 30 % of all WBC's - 60 to 70 % of all WBC's
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{How many of neutrophilic bands are in the blood? - 0 to 1 % of all WBC's + 2 to 5 % of all WBC's - 60 to 70 % of all WBC's - 20 to 30 % of all WBC's
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 * It's a trap! Bands are immature/young neutrophils only.

{How many of neutrophils are in the blood? - 0 to 1 % of all WBC's - 3 to 5 % of all WBC's - 20 to 30 % of all WBC's + 60 to 70 % of all WBC's
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{How many platelets (trombocytes) are in the blood? - 15 000 to 40 000 in mm³ + 150 000 to 400 000 in mm³ - 1.5 000 000 to 4 000 000 in mm³ - 15 000 000 to 40 000 000 in mm³
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{Which important compounds are inside specific granules of basophlis? + Heparine a histamine - Kolagenases - Defensins - Lysozym
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{In which stage occur changes of nuclear morphology which are hallmark of granulocytes? + Metamyelocyte - Promyelocyte - Myeloblaste - Myelocyte
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{In which stage starts production of specific granules? - Metamyelocyte + Promyelocyte - Myeloblaste - Myelocyte
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{Which stage of development of red blood cells is last stage sensitive to erythropoietin (EPO)? - Polychromatophilic erythroblast - Ortochromatophilic erythroblast - Basophilic erythroblast + Proerythroblast
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{Life-span of the red blood cell is around: - 3 to 5 days - 50 days - 80 days + 120 days
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{Main difference between the blood plasma and serum is: - Plasma does not contain proteins involved in blood clotting + Serum does not contain proteins involved in blood clotting - Plasma does not contain albumin and prealbumin - Serum does not contain albumin and prealbumin
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{Major basic protein (MBP) is main part of specific granules of: - All granulocytes - Neutrophlis + Eosinophils - Basophils
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{How is called pathological condition where red blood cells of pathological shapes are present? + Poikilocytosis - Anisocytosis - Polycytaemia - Anaemia
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{Platelets (trombocytes) are not assumed to be cells because: - Bad formulation of the question, platelets are cells + They are fragments of cytoplasm of the megakaryocyte - It was states so in the past - They have no nuclei
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{Which of following statements about platelets is not true? - alpha (α) granules contain proteins involved in blood clotting - delta (δ) granules contain ATP. ADP. serotonin and calcium - lamda (λ) granules contain hydrolytic enzymes + mu (µ) granules contain myeloperoxidase
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{In which structure is first site of production of red blood cells in the embryo? + Wall of the yolk sack - Bone marrow - Kidney - Liver
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{The best definition of the hematocrit (HCT) is: + Volume percentage of the blood occupied by formed blood elements - Mass percentage of the blood occupied by formed blood elements - Total volume of the blood occupied by formed blood elements - Total mass of the blood occupied by formed blood elements
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{Which anions are the most common in the blood plasma? - SO42- a Cl- - H2PO4- a HSiO4- + Cl- a HCO3- - HCO3- a HSiO4-
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{Which cation has the highest concentration in the blood plasma? - Ca2+ - Mg2+ + Na+ - K+
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{Which is a diameter of the monocyte? - 6 to 8 μm - 10 to 12 μm + 12 to 20 μm - 16 to 18 μm
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{Which is a diameter of the neutrophil? - 6 to 8 μm + 10 to 12 μm - 12 to 20 μm - 16 to 18 μm
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{What is a leukocyte? - Activated white blood cell - Quiescent white blood cell - Immature white blood cell + Any white blood cell
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{What is main function of buffer systems in the blood? - Blood buffer is curiosity of biophysical chemistry, but it is out of physiological importance - They are involved in regulation of pH on value related to the actual need of the organism + They are involved in regulation of pH on strict value - There is nothing like buffers inside the blood
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{Which hormone or cytokine simulates formation of platelets? + Trombopoietin - Erytropoietin - Interleukin 6 - Vasopresin
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{Which hormone or cytokine simulates formation of red blood cells? + Erytropoietin (Epo) - Interleukin 1 (IL 1) - Interleukin 6 (IL 6) - Vasopresin
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{Which hormone or cytokine simulates maturation of granulocytes? - SCF (stem cell factor) - Interleukin 5 (IL 5) - Angiotensin + GM-CSF
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{Which of below mentioned cells is not able to undergo mitosis? + Orthochromatophilic erythroblast - Polychromatophilic erythroblast - Bazophilic erythroblast - Proerythroblast
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{Which of following cells is the least differentiated? - Metamyelocyte - Promyelocyte + Myeloblast - Myelocyte
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{Which of statements below describes B lymphocytes the best? - B lymphocytes has nucleus composed of lobules + B lymphocytes are precursors of plasma cells - B lymphocytes has fagocytic activity - B lymphocytes produce antibodies
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{Which of statements below describes T lymphocytes the best? + We have different types of T lymphocytes according to their function - Mature T lymphocytes are released from the bone marrow - T lymphocytes has nucleus composed of lobules - T lymphocytes are usually two-nucleated
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{Which statement about development of the megakaryocyte is correct? - It is a result of both endomitosis and fusion of precursor cells, but endomitosis dominates - It is a result of both endomitosis and fusion of precursor cells, but fusion dominates + It is a result of endomitotic division of precursor cell - It is a result of fusion of precursor cells
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{Which statement about monocytes is false? + Except in very exceptional cases. they have a round nucleus - They circulate in the peripheral blood few days only - They can differentiate in macrophages - They have 15 to 20 μm in diameter
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{Which type of tissue serves as a supportive structure for hematopoiesis in the bone marrow? - Jelly-like connective tissue + Reticular connective tissue - Elastic connective tissue - Connective tissue proper
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