Morphine intoxication

Opiates are natural substances from opium (juice from unripe poppies). These are morphine, heroin , codeine , etc. They are substances that stimulate opiate - endorphin receptors in the CNS , have a sedative and analgesic effect.

Overdose
In case of overdose, there is a depression of consciousness, depression of the respiratory center (brachypnea, apnea) in the medulla oblongata and death. The effect of opiates peaks in 2-3 hours after ingestion.

Clinical picture

 * Euphoria, Miosis (like pinheads),
 * somnolence,
 * Hypotension, Bradycardia,
 * itchy skin,
 * nausea, vomiting, hypotension,
 * decrease in intestinal motility, constipation.

Therapy
The antidote is the specific opioid antagonist naloxone (Intrenon®), naltrexone


 * We give it for signs of respiratory depression, even 0.1 mg after 2 minutes to a dose of 2 mg;

in more severe conditions UPV is required, in case of pulmonary edema oxygen and PEEP.

Related articles

 * Substance abuse
 * Opioid analgesics