Bacitracin

It is a topical polypeptide antibiotics, the mechanism of action of which lies in the inhibition of the formation of the bacterial wall. When applied topically, it is excellently tolerated. A small incidence of resistance is observed.

Spectrum
Includes gram positive cocci and rods.

Indication
In combination with neomycin sulphate, it forms Framycoin, of which it adds a gram-positive spectrum (neomycin acts on gram-negative microbes and staphylococci).

Side effects
They are similar to neomycin (mainly nephrotoxicity). Systemic absorption is undesirable.

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