Nelson syndrome

A relatively rare pituitary adenoma that occurs in patients after adrenal removal, which is increasingly producing ACTH. As a result of adrenalectomy, feedback inhibition of CRH by cortisol is lost, thus increasing hypothalamic CRH secretion and thus ACTH overproduction.

The first symptoms may include visual field loss and hyperpigmentation.

Related articles

 * Hypothalamic-pituitary system

Source

 * KLENER, Pavel. Vnitřní lékařství. 4. vydání. Praha : Galén : Karolinum, c2011. 1174 s. ISBN 978-80-7262-705-9.
 * VOKURKA, Martin a Jan HUGO, et al. Velký lékařský slovník [online] . 8. vydání. Praha : Maxdorf, 2009. 1144 s. Dostupné také z . ISBN 978-80-7345-166-0.