Sarcoidosis of lymphatic system

Sarcoidosis is a multisystem disease of unknown cause. It most often affects young and middle-aged people. It is often manifested by bilateral hilar adenopathy (BHL), pulmonary infiltrates, and ocular and skin lesions. The liver,spleen, lymph nodes, salivary glands, heart, nervous system, muscles, bones and other organs can also be affected.

Epidemiology
Hyl lymphadenopathy is present in 90% of patients. Patients with sarcoidosis account for 74% of all BHL patients.

5–30% of patients have extrauterine lymph node involvement (10.5% in our country).

Splenomegaly was found on CT in 6% of patients.

Symptoms
Affected peripheral lymphnodesare small, motile and painless, do not ulcerate, do not form fistulas.  Abdominal lymphadenopathy  is present as multiple enlarged paraaortic, paracaval and portal lymph nodes. Isolated granulomatoid lymph node involvement is not sufficient for a certain diagnosis of sarcoidosis. It is referred to as GLUS (granulomatous lesions of unknown significance).

Disability spleen can cause disorders in blood count.

Diagnostics
In X-ray lungs, the most characteristic finding is BHL, which may also be a sign of malignancy (lymphoma, bronchogenic carcinoma, extracorporeal tumors).

Related articles

 * Sarcoidosis
 * Sarcoidosis (pathology)
 * Sarcoidosis (internal)

Source

 * ANTON, Jan. Lecture materials "Sarkoidóza".