Inversion

Inversion is a form of chromosome mutation – structural abnormality.


 * Typical for inversion is two breaks in different parts of the chromosome. The newly created segment rearranges itself and is reversed.
 * Inversion was discovered in 1921.
 * Although we still don´t know why inversion exists, we know that it is the most important mechanism of reorganizing the genome.
 * We recognize 2 types of inversion:
 * 1) pericentric – causes deletions, insertions or abnormal centromeres, with a breakpoint in each chromosomal arm.
 * 2) paracentric – is the more common type, it is less harmful for its carrier as it does not involve the centromere.


 * Inversion suppresses the recombination process.

Related articles

 * Chromosome Abnormalities
 * Karyotype