Uterine Cancer (pathology)

Uterine cancers include:  'leiomyosarcoma, stromal sarcoma, uterine carcinoma,' 'carcinosarcoma' '.

Leiomyosarcoma
It is a  malignant tumor  'arising from smooth muscle cells. It is rarer than its benign variant - leiomyoma. Macroscopically, it's a  solid knot of  bright color '' and soft consistency. Sometimes it is sharply demarcated, other times it infiltrates the surroundings. We often see necrosis and other regressive changes in it. In the microscope, we see higher cellularity, nuclear polymorphism and mitotic activity in this tumor. After removal,  'often relapses'  and may even  'hematogenously metastasize'  [ metastasize ] The prognosis depends on the degree of tumor differentiation, with approximately 40% of patients surviving 5 years.''

Stromal sarcoma
The Endometrium during the Menstrual Cycle undergoes many changes and has tremendous proliferative activity. Tumors that originate in the endometrium can be benign, borderline, or malignant. Stromal sarcoma is the  most important  of endometrial tumors.

This tumor is dangerous because it grows  'diffusely' ,  'infiltrates between the bundles myometria' , penetrates both the lymphatic and blood vessels. In addition, it passes into the uterine cavity just like Uterine polyp. All of these properties suggest that this tumor is' 'highly invasive'  and therefore is being prevented  [hysterectomy]]. However, recurrences occur, with hematogenous and lymphatic metastases appearing in approximately 15% of cases. According to proliferative activity we divide:
 * low-grade - low malignant,
 * high-grade - highly malignant.