Disorders of myelination/Repetitorium

Concepts: Formation and function of the myelin sheath

Demyelinating and dysmyelinating disorders

 * Slowing of AP propagation - desynchronization of conduction
 * Incomplete nerve fiber isolation - AP propagation with decrement - AP skipping
 * Limitation of mechanical protection

Central and peripheral demyelination
Major causes
 * Sclerosis multiplex
 * Diabetes mellitus

Related articles

 * Multiple Sclerosis
 * Chronic complications of diabetes