Portal:Exam Topics in Pharmacology (3. LF UK)

General

 * 1) Drugs - drug names, drug regulation, FDA, SPC
 * 2) Routes of drug administration, first-pass effect
 * 3) Absorption of drugs, bioavailability
 * 4) Distribution of drugs, volume of distribution
 * 5) Drug biotransformation, enzyme induction
 * 6) Elimination of drugs, excretion of drugs, enterohepatic circulation
 * 7) Pharmacokinetic variables: volume of distribution, clearance, half-life
 * 8) Clinical relevance of pharmacokinetic variables: half-life, volume of distribution, clearance
 * 9) Transfer of drugs across membranes
 * 10) Major sites of action of drugs: receptors, enzymes, ion channels, transporters
 * 11) Drug- receptor interactions: drug agonists, antagonists
 * 12) Ligand-gated channels, G proteins, second messengers
 * 13) Relation between drug dose & response, LD50, ED50, therapeutic index
 * 14) Half-life and the time required to reach steady state after a repeated administration
 * 15) Tolerance, tachyphylaxis
 * 16) Drug interactions
 * 17) Drug allergy, anaphylactic shock, bronchospasm, skin reactions
 * 18) Teratogenic effects of drugs
 * 19) Prescribing for the elderly, dosage in children
 * 20) Adverse drug reactions, serious ADRs, reporting ADRs
 * 21) Pre-clinical evaluation of new drugs
 * 22) Clinical evaluation of new drugs
 * 23) Therapeutic drug monitoring (TDM). Sources of drug information

Drug groups

 * 1) Antihypertensive agents
 * 2) Diuretics
 * 3) Beta-adrenergic antagonists [beta-blockers]
 * 4) Calcium channel blockers
 * 5) ACE inhibitors and angiotensin II inhibitors
 * 6) Centrally acting antihypertensive agents, alfa –adrenoceptor-blocking agents
 * 7) Drugs used to treat angina pectoris
 * 8) Nitrates
 * 9) Vasodilators
 * 10) Positive inotropic drugs and sympathomimetic drugs used in the treatment of cardiovasculars disorders
 * 11) Positive inotropic drugs
 * 12)  drugs
 * 13) Antihistamines
 * 14) Ergot alkaloids
 * 15) Polypeptides
 * 16) Eicosanoids, prostaglandins
 * 17) Drugs used in asthma
 * 18) Bronchodilators
 * 19) Expectorants
 * 20) Anxiolytic
 * 21) Anxiolytic agents
 * 22) Benzodiazepines
 * 23) Sedative-hypnotics
 * 24) Ethanol
 * 25) Antiepileptic drugs
 * 26) General anesthetics
 * 27) Local anesthetics
 * 28) Skeletal muscle relaxants
 * 29) Drugs for Parkinson's disease
 * 30) Antipsychotic agents (neuroleptics)
 * 31)  Phenothiazines
 * 32) Lithium
 * 33)  Antidepressant agents
 * 34) Opioid analgesics & antagonists
 * 35) Nonopioid analgesics
 * 36)  Antimigraine drugs
 * 37)  Drugs of abuse
 * 38)  Agents used in anemias
 * 39)  Anticoagulant drugs & their antagonists
 * 40)  Fibrinolytic drugs, antiplatelet drugs
 * 41)  Agents used in hyperlipidemia . Plasma substitutes,
 * 42)  Non-steroidal antiinflamatory drugs
 * 43)  Drugs used in gout
 * 44)  Hypothalamic & pituitary hormones
 * 45)  Thyroid & antithyroid drugs
 * 46)  Corticosteroids
 * 47)  Gonadal hormones & inhibitors
 * 48)  Contraceptives
 * 49)  Pancreatic hormones & antidiabetic drugs
 * 50)  Drugs affecting bone metabolism
 * 51) Penicillins
 * 52)  Basic penicillins
 * 53)  Broad spectrum penicillins
 * 54)  Cephalosporins
 * 55)  Antibiotics against Staphylococcus
 * 56)  Tetracyclines
 * 57)  Aminoglycosides
 * 58)  Macrolides
 * 59)  Antimycobacterial drugs
 * 60)  Sulfonamides and trimethoprim
 * 61)  Antifungal agents
 * 62)  Chemotherapy of urinary tract infections
 * 63)  Treatment of trichomoniasis, Antimalarial agents
 * 64)  Antiviral agents
 * 65)  Antihelmintic drugs, ectoparasiticides
 * 66)  Cancer chemotherapy
 * 67)  Immunosuppressive and immunomodulating agents
 * 68)  Chelators
 * 69)  Drugs used in glaucoma therapy
 * 70)  Dermatologic agents
 * 71)  Drugs used in rhino- and laryngology
 * 72)  Drugs used in dermatology
 * 73)  Drugs used in the treatment for acne
 * 74)  Topical corticosteroids
 * 75)  Drugs used in gastrointestinal disease
 * 76)  Drugs used in acid-peptic disease
 * 77)  Antiemetics
 * 78)  Laxatives
 * 79)  Antidiarrheal agents
 * 80)  Spasmolytic agents and spasmoanalgesics
 * 81)  Vitamins
 * 82)  Disinfectants and antiseptics
 * 83)  Calcium, magnesium, potassium, sodium, Fluor
 * 84) Homeopathy
 * 85)  Drugs used in the obesity treatment
 * 86)  Uterotonics, tocolytic agents
 * 87) Specific antidotes used in management of the poisoned patient