Enterovirus diseases

Enteroviruses

 * They occur worldwide, causing diseases very often.
 * together with rinoviruses and aphtoviruses, they belong to the RNA family Picornaviridae.
 * Divided into:
 * Polioviruses,
 * Coxsackie,
 * ECHO viruses.
 * EV 68 − 71

Source of infection and symptoms

 * Human, transmission mainly by the fecal-oral route;
 * often in summer;
 * most often infected – preschool children;
 * place of multiplication – nasopharyngeal mucosa, tonsils or small intestine → nodules→ primary viremia→ into various organs, multiply→ secondary viremia;
 * the most prominent pathogenic property – neurotropicity (mainly polioviruses);
 * myotropicity (coxsackie) – myositis, dermotropicity;
 * the infection can be stopped at various levels by immunity – often at the site of the first multiplication,
 * long-term immunity develops after infection;
 * clinical manifestations are very varied, about 90 % are inapparent;
 * the same serotype may cause completely different symptoms in different individuals (ECHO9 may cause serous meningitis in one fever, serous menigitis in another, and rash in another);
 * EV 70 is one of the causes of acute hemorragic conjunctivitis
 * EV 71 is one of the causative agents of aseptic meningitis, encephalitis, polyneuritis and respiratory disesases

related articles

 * Enterovirovirus rashes

Source

 * BENEŠ, Jiří. Studijní materiály [online]. ©2007. [cit. 2010].