Human herpesvirus 8

{{Infobox - virus | name = Human herpesvirus 8
 * picture = Kaposi Sarcoma Lesions.jpg
 * caption = Kaposi sarcoma
 * family = Herpesviridae
 * nucleic acid = dsDNA
 * source = human
 * transmission = via sexual intercourse, blood
 * occurrence = ubiquitous
 * disease = Kaposi sarcoma (HIV{{sup|+}}), other malignities (angiosarcoma ), [[Castleman's disease]
 * diagnostic = serology, detection of antibodies against nuclear antigen, HHV-8 DNA
 * treatment = to date there is no causal therapy available 'HHV-8'  ( Human Herpesvirus 8 ), also referred to as  'KSHV'  ( Kaposi sarcoma-associated herpesvirus ), is a dsDNA virus from family  Herpesviridae .


 * Described in patients with immune defect (HIV).
 * In immunodeficiency causes Kaposi's sarcoma (mesenchymal malignant vascular tumor).
 * Other diseases caused by the virus include "primary exudative lymphoma" (when malignant B-lymphoma develops) or Castleman's disease.
 * It also occurs in immunocompetent persons, in whom it causes only latent infection.
 * Current status diagnostics using PCR only.
 * Serological diagnostics: IgG antibodies - anamnestic.

Related articles

 * Kaposi sarcoma

Source

 * ŽAMPACHOVÁ, Eva. Přednášky a materiály dr. Žampachové ke stažení [online]. [cit. 2012-01-26]. < http://mujweb.cz/zampach/motol/?redirected=1521314685 >.