Precancerous conditions in dermatology


 * in a broader sense, they are chronic manifestations of various origins, long - term irritation stimulates the tissue to proliferate (chronic ulcers, lupus vulgaris, scars, etc.)
 * in these processes and their surroundings there are warty proliferating granulations - they mimic the tumor - pseudoepitheliomatous hyperplasia or paratypic proliferation
 * in the narrower sense - separate clinical units, from which the tumor develops more often with a sufficiently long duration ...

Keratoma senile
= solar keratosis, actinic keratotic


 * in the elderly in places exposed to the sun and external influences, manifestations usually such as degeneratio cutis senilis
 * epidermal dysplasia
 * sharply demarcated deposit of gray to red color, rough surface, covered with hyperkeratotic scales, later becomes wet, then bleeds until ulcerated
 * turns into cancer (mainly carcinoma spinecellulare)

Cornu cutaneum

 * they do not differ from the keratom, a horn-like formation grows on the surface, even a few cm, the base can change into spinocelular carcinoma

Leukoplakia

 * typical precancerous mucosa, whitish, opalescent, sharply demarcated deposits
 * Later, the bearing can be:
 * elevated - leukoplakia simplex,
 * with a rough to verrucous surface - leukoplakia verrucosa,
 * can erode - leukoplakia erosiva.
 * influences - smoking, mechanical irritation, chemical influences
 * must distinguish from lichen ruber!

Lentigo maligna

 * irregular brown to black deposit, irregular pigmentation
 * slow enlargement to the area
 * mainly face, men around 60 years
 * consequence of long-term exposure to UV radiation
 * proliferation of atypical melanocytes in the epidermis
 * risk of transition to malignant melanoma - lentigo maligna melanoma

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