Minerals in Human Nutrition

= Role of Minerals in Human Nutrition (Ca, P, Mg, Na, K): sources, excess, deficiency'=

Calcium

Is present mainly as hydroxyapatite in bones and teeth with phosphorus at a ratio of 2:1, it reduces neuromuscular excitation, important for heart conduction systém, Essentials for blood coagulation systém and prevention of colorectal carcinoma. The richest sources are milk and dairy products, also leafy green vegetables, pulses and salmon. Deficienty results in osteomalatia, osteoporosis, rickets, increased neuromuscular iritability, tachycardia, increased blood clotting and increased carcinoma of colon. Excess intake results in renal insufficiency, vascular and soft tissue calcification, hypercalciuria and kidney stones. Children need 2‐4 times more calcium per kg body weight thanadults, higher intake recommended during preadolescence, puberty, pregnancy, lactation. Requirement– 800mg/day

Phosphorus

Together with calcium it forms phospholipids, phosphoproteins, nucleic acids, enzymes and macroergic bonds(ATP). Its best source is milk, dairy products, egg yolks and pulses. Its deficienty is very rare but secondary deficienty may be due to use of antacids. Excess increases the risk of osteoporosis. With advanced age renal function declines, and high phosphate intake can increaserisk of bone demineralisation. Infants 400mg, children 900‐1200mg, pregnant women 1500mg, lactating women 1800mg/ day

Magnesium

Role in all biosynthetic processes: glycolysis, formation of cyclic AMP, energy dependant membrane transport nd transmission of the genetic code.Activates more than 300 enzymes Reduces neuromuscular excitation and effects protein,nucleic acid and cholesterol synthesis. Best dietary source is chlorophyll ( green plants, pulses, nuts).No deficiency in people consuming natural diets.Excess causes diarrhea and bradycardia. Infants 10mg/kg, children 250mg, adults 350mg, pregnant and lactating women 450mg

Sodium

Role in osmotic pressure, acid base balance, acid and nerve irritability. Source – table salt and salty food, also meat, eggs, meat.Deficiency – hyponatremia (<145mmol/l), muscle weakness, paralysis and impaired heart function.Excess intake leads to hypernatremia emg from dehydration or kidney failure.Recommended 6g/day.

Potassium

Essential for muscle activity, particularly of heart. Source‐ soya, beans, apricot, potato,tomato, carrot, banana. Deficiency – develops after vomiting, diarrhoea, perspiration, high protein diet‐ irritability, muscle weakness, tachycardia. Excess‐  dehydration, shock with decrease urinary out put –inhibited cardiac activity, weakness, pins and needles in legs, confusion, difficulty breathing and speaking, nausea. Requirement‐ children 0.5‐ 4.5g, adults 1.8‐5.6g

= REFERENCE=
 * 1) BENCKO, Vladimir, et al. Hygiene and Epidemiology : Selected Chapters. 2nd edition. Prague. 2008. ISBN 80-246-0793-X.
 * 2) Lener, J. et al. Medical Hygiene. Karolinum, Praha 1997.