The principle of negative feedback in endocrinology

The basic principle in endocrine regulation is feedback. The most common type is negative feedback, where the induced change reduces the activity of the system.

Simple feedback
hormone production is regulated by a change in the chemical composition of the blood caused by the hormone:


 * blood glucose ( insulin and glucagon )
 * calcemia (calcitonin a PTH)
 * natremia ( aldosterone )

The complex feedback
Hormone production is regulated by the concentration of the hormone in the peripheral blood, it is mainly applied to hormones that are affected by the superior endocrine gland:


 * TSH
 * ACTH