Lymph node (SFLT)

Nodule pith
Description: B-lymphocytes predominate in the medulla, as in the follicles of the cortex, and is characterized by darker branching processes of lymphatic tissue (medullary cords) separated from each other by lighter medullary lymphoid sinuses that drain lymph.

Subcapsular sinus


Description: The space beneath the fibrous capsule where afferent lymphatic vessels deliver lymph.

General overview - lymph node


Description: In the upper part of the preparation, we can see a fibrous sheath, under which is the subcapsular sinus. This is followed by the outer cortical region, which contains spherical lymph nodes (mostly composed of B-lymphocytes). Below the outer cortical area we find the inner cortical area, composed mainly of T-lymphocytes, which only rarely contains lymph nodes. The central part is the medulla, the description of which is on a special specimen.

Detail of bark
Description: Secondary lymph nodes are composed of an inner (lighter) germinal center and a mantle zone (darker) around it. The lighter staining of the germinal center is due to a smaller number of activated B-lymphocytes, the cytoplasm of which is more voluminous and the nucleus is stained lighter.

Immune System

 * Lymph Node (SFLT)


 * Spleen (SFLT)


 * Palatine tonsil (SFLT)

Links

 * Histological atlas (3. LF UK)