Peroxisomal leukodystrophy

Peroxisomal leukodystrophies are leukodystrophies, that are caused by a malfunction of peroxisomes, subcellular organelles involved in many metabolic pathways - the formation and degradation of hydrogen peroxide (catalase), fatty acid oxidation, cholesterol and dolichol synthesis, etc.

Peroxisomal disorders can be divided into two categories:
 * disorder of peroxisomal biogenesis − typical representatives are Zellweger syndrome and neonatal adrenoleukodystrophy
 * defects of individual peroxisome enzymes − representative is X-linked adrenoleukodystrophy.

Related articles

 * Peroxisome
 * Peroxisomal disease
 * Leukodystrophy
 * X-linked adrenoleukodystrophy
 * Neonatal adrenoleukodystrophy
 * Zellweger syndrome