Benign salivary gland tumors


 * Benign salivary gland tumors are highly variable.
 * Occurrence is independent of gender.
 * They usually grow slowly and painlessly.
 * Epithelia are more common than mesenchyme.
 * Therapy is surgical.
 * Pleomorphic adenoma (mixed tumor, myxochondroepithelioma) and papillary cystadenolymphoma (Warthin's tumor) are the most common.
 * We include several types of tumors here:

Pleomorphic adenoma

 * The so-called myxochondroepithelioma.
 * The most common tumor of the salivary glands.
 * Epithelial tumor, most often in the glandula parotis (and also the most common gl. parotis tumor).
 * Mainly in older and middle age, it is slowly growing.


 * Possible relapses.
 * The tumor often grows into the capsule, which increases the possibility of malignancy.
 * It manifests clinically as a painless swelling.
 * Several components alternate in the histological picture - an epitheliomatous component with a trabecular, ductal, acinous or solid arrangement, as well as a myxoid and chondroid component.

Papillary cystadenolymphoma (Warthin's tumor)

 * The second most common benign salivary gland tumor.
 * Occurrence mainly in gl. parotid and submandibular glands (9% of tumors in gl. parotid).
 * After the age of 40, more often men.
 * It is usually circumscribed, rigid, well mobile against the substrate, spherical, on sonography it can imitate a cyst.
 * Grows slowly.
 * 10% recurrence, malignant reversal is very rare.
 * It arises from the proliferation of epithelial inclusions in the intraparotic lymph nodes.
 * The characteristic histological picture is dominated by a double-layered epithelium with nuclei facing the lumen, the stroma is made up of lymphatic tissue.

Basal cell adenoma

 * 70% in gl. parotid, 20% minor glands of the lip.
 * Peak incidence in the 7th decade.
 * Possible transition to basal cell carcinoma.

Myoepithelioma

 * Rare.
 * Mainly affects gl. parotid gland.
 * May malign.
 * Unlike pleomorphic adenoma, they do not form ductal structures.

Oncocytoma

 * Occurrence in the 6th to 7th decade, more often in women.
 * Grows slowly, is mobile, small (up to 2 cm).
 * Forms a case, grey-red in section.
 * Recurrences do not occur, malignization only very rarely.
 * In the histological image, eosinophilic finely granular cells with an increased number of mitochondria are visible.

Canalicular adenoma

 * Incidence over 50 years.
 * Usually in the upper lip.

Sebaceous adenoma

 * Rare.
 * Well circumscribed, cystic, varying in size.

Papilloma ductulation

 * Not very common.
 * It arises from the epithelium of the ducts of small salivary glands.

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 * Salivary glands
 * Malignant salivary gland tumors