Myeloproliferative diseases

Myeloproliferative diseases are a group of sharply demarcated disease units that are expected to transform a pluripotent stem cell. This results in uncontrolled proliferation and differentiation of this transformed cell. A pathological clone often suppresses the production of hematopoietic cells from normal clones. There is also a significant increase in blood elements in one row and at the same time a less significant increase in other rows.

Myeloproliferative diseases include the following units: chronic myeloid leukemia, polycythemia vera, essential thrombocythemia, primary myelofibrosis, systemic mastocytosis. systémová mastocytóza.

Classification of myeloproliferative diseases
The difference between these diseases lies in the hematopoietic lineage into which the cells differentiate. There is no sharp line between clinical units.

FAB classification includes among myeloproliferative diseases: In addition, the WHO classification according to new findings includes:
 * Chronic myeloid leukemia (CML);
 * True polycythemia (PV);
 * Essential thrombocythaemia (ET);
 * Primary myelofibrosis (PMF).
 * Chronic neutrophilic leukemia (CNL);
 * Chronic eosinophilic leukemia (CELL, NOS)).

= Polycytemia vera =

= Chronic myeloid leukemia =

= Primary myelofibrosis =

= Essential thrombocythemia =

= Systemic mastocytosis =