Metabolic osteopathy

Metabolic osteopathies are diseases caused by disturbances in the balance between bone formation and resorption and disturbances in bone mineralization → osteopenia and decreased bone mass (osteoporosis, osteomalacia) or bone sclerotization and increased bone mass (Paget's disease, osteopetrosis). These osteopathies are caused by bone cell dysfunction, genetic abnormalities (defects in the synthesis of collagen I etc.), increased expression of bone morphogenetic proteins, kidney function disorders, endocrinopathies, tumor secretion of substances affecting bone metabolism

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