Talk:Echovirus

They are RNA viruses, belonging to the genus Aphtovirus and contain 33 different serotypes.

Diseases
Most of the diseases are severe.
 * most infections are inapparent (without clinical manifestations).
 * about 5 % of infections have clinical symptoms: febrile illness, myalgia, exanthema, meningitis, encephalitis, respiratory and digestive system diseases, pericarditis, hepatitis, pancreatitis,...

Patogeneze

 * gate for entry: mainly through food, rarely through respiratory system
 * multiplication in cells
 * spread by hematogenous route
 * clinical consequences depend on the site virus attachment and the individual's susceptibility.
 * virus je intenzivně vylučován z napadnuté sliznice.

Diagnosis

 * incubation from nasopharyngeal swabs, from stool or from cerebrospinal fluid on cell cultures from monkey kidneys or mice.
 * serological diagnosis by neutralization test.

Epidemiology
The source of the virus is an infected human, who is infectious at the end of the incubation period (3 to 7 days). The disease occurs mainly in summer and early autumn.