Repair and regeneration

Healing in general Healing occurs when injured tissues are incapable of complete restitution (regeneration). In this scenario, repair occurs by laying down of connective (fibrous) tissue, that results in scar formation. Repair occurs within 24 hours of injury by the emigration of fibroblasts and the induction of fibroblast and endothelial cell proliferation. By 3 to 5 days, granulation tissue is apparent, characterized by new delicate cappilaries (angiogenesis). Granulation tissue then progressively accumulates connective tissue matrix, eventually resulting in the formation of a scar.

Healing of a bone fracture Generally bone fracture treatment consists of a doctor pushing dislocated bones back into place and then waiting for the bone's natural healing process to occur.