Non-epithelial tumors of the ovary

Nonepithelial ovarian tumors can be either tumors of germ cell or tumors of stromal and germline cells' (sex cord- gonadal stromal tumors).

Germ cell tumors
There can be purely germline tumors and tumors mixed with germline tumors. Purely germinal can be :
 * dysgerminoma - is the most common malignant germinal tumor and affects both ovaries in 20%, is chemo and radiosensitive (treated with chemotherapy); there is a high risk of developing malignant dysgerminoma in any (phenotypic) woman with a 46,XY karyotype or the presence of SRY - this is an indication for removal of the gonads ;
 * yolk sac tumor;
 * embryonic carcinoma;
 * polyembrome;
 * choriocarcinoma;
 * teratoma.

Sex cord-gonadal stromal tumors
They may be of germline tissue or stromal tissue or both (mixed) and may produce either estrogens, androgens or both (gynandroblastoma). They are distinguished by:
 * granulosa tumors;
 * thecomas/fibromas;
 * androblastomas (Sertoli tumor, Leydig tumor, Sertoli-Leydig tumor);
 * gynandroblastomas (mixed male and female, may be mixed stromal and sex-cord, or one of these tissues).

Source

 * ws:Neepitelové nádory ovaria

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