Verrucous Carcinoma

Verrucous carcinoma (Carcinoma verrucosum) is a highly differentiated variant of squamous cell carcinoma of the skin, which is characterized by slow growth and a warty surface.

It is an invasive carcinoma, but has very little tendency to metastasize.

Epidemiology
It occurs mainly in elderly patients in areas with scars, chronic wounds, and chronic venous insufficiency. In some cases, an association with HPV 6 and 11 has been demonstrated.

Clinical Picture
There are four forms, mostly according to location.

Diagnosis
Histological. It is an asymmetrically proliferating formation into the epidermis. Contains keratin-filled crypts.

Therapy
Surgical treatment is necessary. It is supplemented by radiotherapy, chemotherapy, laser destruction of the tumor, total treatment with retinoids, or interferons.

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