Leukocytosis

Definition and distribution
Leukocytosis is an increased number of leukocytes in a person's blood. It can be caused by a reactive (secondary) or malignant cause. Depending on the type of leukocyte, we recognize the following types of white line defects, which are also causes of leukocytosis:


 * Neutrophilia – an increase in the absolute number of neutrophils in the peripheral blood above the limit of 7.5 × 109/l.
 * Lymphocytosis – an increase in the number of lymphocytes in the peripheral blood above the limit of 4.5 × 109/l.
 * Basophilia – an increase in the number of basophils in the peripheral blood above the limit of 0.1 × 109/l.
 * Monocytosis – an increase in the number of monocytes in the peripheral blood above the limit of 0.8 × 109/l.
 * Eosinophils – an increase in the number of eosinophils in the peripheral blood above the limit of 0.25 × 109/l.

Neutrophilia
Neutrophilia can be caused by a number of causes. These causes include:
 * infection (bacterial, fungal, spirochete and others),
 * inflammation (vasculitis and others),
 * physical exertion, pregnancy,
 * severe metabolic acidosis (diabetic ketoacidosis),
 * smoking



Lymfocytosis
Lymphocytosis is usually caused by an acute viral infection or a chronic infection. Other various causes include:
 * malignancies (leukemia and lymphomas),
 * injuries
 * excessive physical exertion
 * stress lymphocytosis (after a myocardial infarction or with lymphocytosis after adrenaline).

Bazophilia
Most of the causes of basophilia are life-threatening, which is why early diagnosis and then prompt treatment are important. These causes include:
 * inflammatory disease (ulcerative colitis and others),
 * medications (e.g. estrogens and others),
 * irradiation,
 * hyperlipidemia

Monocytosis
The causes of monocytosis also usually include life-threatening conditions, early diagnosis and then quickly started treatment is important. Such causes include:
 * infection (malaria, trypanosomiasis),
 * tuberculosis,
 * typhoid,


 * Hodgkin's lymphoma,
 * hemolytic anemia.

Eozinofilia
Eosinophilia can be caused by:
 * allergic reaction,
 * parasitic disease
 * condition after infectious mononucleosis

Diagnose
Leukocytosis is detected as part of a differential blood count examination.

Related articles

 * Neutropenia
 * Lymfocytopenia
 * Leukopenia