Böök syndrome

Synonyms: PHC syndrome, aplasia of premolars, hyperhidrosis.

Named after the Swedish geneticist Jan Böök who first described the disease in 1950.

Genetics:
 * OMIM: 112300
 * Inheritance is probably autosomal dominant with high penetrance.

Characteristics:
 * premature greying,
 * palmar and plantar hyperkeratosis,
 * hypodontia,
 * aplasia of premolars.