Csf syndromes

When interpreting the number of cells in the cerebrospinal fluid and the values ​​of the total protein concentration in the cerebrospinal fluid, the following syndromes are described:
 * Syndrome of proteinocytological dissociation - increased concentration of total proteins (hyperproteinorachia) and normal number of elements (oligocytosis) - a typical finding for blockage of cerebrospinal fluid channels, e.g. by a tumor, sometimes in multiple sclerosis and in the terminal phase of inflammation.


 * Syndrome of proteinocytological association - increased concentration of total protein (hyperproteinorachia) and multiplication of elements (pleocytosis). It typically occurs in neuroinfections.


 * Cytoprotein dissociation syndrome - increased number of elements (pleocytosis) and normal protein concentration (normoproteinorachia) - a frequent finding in the initial phase of inflammation.
 * {| class="wikitable" style="text-align:center"

! colspan=7 | Differential diagnosis of cerebrospinal fluid findings in the most common infectious diseases of the CNS ! Illness ! Number of cells in μl ! Cell type ! Total protein ! Glucose ! Chlorides ! Cultivation
 * Acute bacterial meningitis || 500-20&thinsp;000 || no || ↑↑ || ↓ to ↓↓ || norm || +
 * Acute viral meningitis || 50-1000 || lym, mono || (↑) || (↓) || norm || (+)
 * Chronic CNS infection || ↑↑ || lym, mono || ↑↑ || ↓↓ || norm ||
 * TB || 50-1000 || lym, neu || ↑↑ || ↓↓ || ↓ || +
 * Brain abscess || 5-100 || no, mono || ↑↑ || norm || norm || −
 * Viral encephalitis || 5-100 || mono || (↑) || norm || norm || −
 * Acute polyradiculoneuritis || norm || mono || ↑↑ || norm || norm || −
 * }
 * Added according to:.
 * Brain abscess || 5-100 || no, mono || ↑↑ || norm || norm || −
 * Viral encephalitis || 5-100 || mono || (↑) || norm || norm || −
 * Acute polyradiculoneuritis || norm || mono || ↑↑ || norm || norm || −
 * }
 * Added according to:.
 * }
 * Added according to:.

Links

 * ws: Likvorové syndromy

Related Articles

 * Cerebrospinal fluid
 * Biochemical examination of cerebrospinal fluid
 * Proteins in cerebrospinal fluid
 * Spectrophotometry of cerebrospinal fluid
 * Cytological examination of cerebrospinal fluid