Non-epithelial ovarian tumors

Non-epithelial ovarian tumors can be either  germ cell tumors, or stromal and germ cell tumors (sex cord-gonadal stromal tumors).

Germinal tumorsy
The tumors may be purely germinal and tumors mixed with germline tumors. Purely germinal can be :
 * dysgerminoma – is the most common malignant germ cell tumor and in 20% it affects both ovaries, t is chemo and radiosensitive (it is treated with chemotherapy); every (phenotypic) woman with karyotype 46, XY or the presence of SRY – is at high risk of developing malignant dysgerminoma - this is an indication to remove gonads ;
 * yolk sac tumor;
 * embryonic carcinoma;
 * polyembrom;
 * choriokarcinom;
 * teratom.

Sex cord-gonadal stromal tumors
They can be from germline tissue, or from stromal tissue, or both (mixed ), and can produce either estrogens, androgens, or both ( gynandroblastoma ). They are distinguished as follows::
 * granulosa tumors;
 * thekomy/fibromy;
 * androblastomas (Sertoli tumor, Leydig tumor, Sertoli-Leydig tumor);
 * gynandroblastomas (mixed male and female, can be mixed stromal and sex-cord, or one of these tissues).

Related articles

 * Ovarian tumors
 * Ovarian cancer
 * Malignant tumors in gynecology