Hyaline dystrophy

In hyaline dystrophy, there is a strengthening of the bonds between the structural components of collagen, which in EM have the appearance of thin, disordered fibrils, with more amorphous protein matter between them.

. Podobá se amyloid, makroskopicky jeho ložiska připomínají chrupavku.

Hyalinně degenerované vazivo (tzv. hyalinizované vazivo – tuhé, zpevněné vazivo) má sklon ke steatóze a ke kalcifikaci (typicky při ateroskleróze). Hyalin se často vyskytuje v jizvách a při chronických zánětech. Při primárně proliferativním zánětu serózních membrán – polyserositis (Curschmannova nemoc) tvoří chrupavčitě tuhá bělavá ložiska např. v pouzdře sleziny – polevová slezina (perisplenitis cartilaginea) nebo na povrchu volných těles v peritoneální dutině (corpus liberum).

Under the light microscope, hyaline appears as an eosinophilic mass. It stains like collagen – pink in HE, blue in blue trichrome. It resembles amyloid, macroscopically its foci resemble cartilage. Hyaline degenerated tissue (so-called hyalinized tissue - stiff, hardened tissue) has a tendency to steatosis and to calcification(typically in atherosclerosis. Hyaline is often found in scars and chronic inflammation. In the case of primarily proliferative inflammation of the serous membranes - polyserositis' (Churchman’s disease) cartilaginous hard whitish deposits are formed, e.g. in the capsule of the spleen - 'coating spleen (perisplenitis cartilage ) or on the surface of free bodies in the peritoneal cavity (''corpus liberum').

related articles

 * Intercellular mass disorders
 * Collagen