Precancers in dermatology


 * in a broader sense, they are chronic manifestations of various origins, long-term irritation stimulates the tissue to proliferate (chronic ulcers, lupus vulgaris, scars, etc.)
 * in and around these processes, there are warty exuberant granulations - mimicking a tumor - pseudoepitheliomatous hyperplasia' or 'paratypic proliferation
 * in the narrower sense of the word – separate clinical units, from which a tumor develops more often if it lasts long enough...

Keratoma senile
= keratosis solaris, keratosis actinica
 * in old people in places exposed to the sun and external influences, manifestations usually like degeneratio cutis senilis'
 * epidermal dysplasia
 * sharply defined focus of gray to red color, rough surface, covered with hyperkeratotic scales, later becomes moist, then bleeds and ulcerates
 * turns into cancer (mainly squamous cell)

Cornu cutaneum

 * does not differ from keratome, a horn-shaped formation grows on the surface, even several cm, the base can change into a spinocele. carcinoma

Leukoplakia

 * typical precancer of mucous membranes, whitish, opalescent, sharply demarcated deposits
 * later the bearing can be:
 * elevated - leukoplakia simplex,
 * with a thickened to verrucous surface - leukoplakia verrucosa,
 * can erode - leukoplakia erosiva.
 * effects of formation - smoking, mechanical irritation, chemical effects,...
 * must distinguish lichen ruber!=== Lentigo maligna ===
 * irregular brown to black deposit, irregular pigmentation
 * slowly expanding into an area
 * mainly face, men around 60 years old
 * the result of long-term exposure to UV radiation
 * proliferation of atypical melanocytes in the epidermis
 * risk of transition to malignant melanoma - lentigo maligna melanoma