Prostatic Specific Antigen

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Prostatic specific antigene is kalikrein-like serotonine protease. It is organ specific tumor marker for prostatic cancer, is produced by secretory epithelial cells .

Normal Value[edit | edit source]

Normal value is < 4 ng/ml, but with exceptions(!), this value changes with age of man.

AGE MEDIAN (ng/ml) Limit value (ng/ml)
40–49 0,7 2,5
50–59 0,9 3,5
60–69 1,4 4,5
>70 1,4 6,5

The value of PSA can be artificially elevated by prostatitis (infection), bicycling, ejaculation, instrumental examination of male urethra or examination of prostate by DRE.[1]

Possible Characteristics of PSA[edit | edit source]

  • free/total PSA
  • PSAD (density) = PSA/body weight
  • PSAV (velocity) = increase per 1 year
  • PSADT (doubling time)

Links[edit | edit source]

Related Articles[edit | edit source]

Bibliography[edit | edit source]

  • DVOŘÁČEK, Jan. Karcinom prostaty [lecture for subject Urology, specialization Generral Medicine, 1. LF UK Charles University in Prague]. Prague. 2012. 

References[edit | edit source]

  1. HANUŠ, Tomáš. Urologie. 1. edition. Prague : Triton, 2011. pp. 133. ISBN 978-80-7387-387-5.