Portal:Exam Topics in Pharmacology (3. LF UK)

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General[edit | edit source]

  1. Drugs - drug names, drug regulation, FDA, SPC
  2. Routes of drug administration, first-pass effect
  3. Absorption of drugs, bioavailability
  4. Distribution of drugs, volume of distribution
  5. Drug biotransformation, enzyme induction
  6. Elimination of drugs, excretion of drugs, enterohepatic circulation
  7. Pharmacokinetic variables: volume of distribution, clearance, half-life
  8. Clinical relevance of pharmacokinetic variables: half-life, volume of distribution, clearance
  9. Transfer of drugs across membranes
  10. Major sites of action of drugs: receptors, enzymes, ion channels, transporters
  11. Drug- receptor interactions: drug agonists, antagonists
  12. Ligand-gated channels, G proteins, second messengers
  13. Relation between drug dose & response, LD50, ED50, therapeutic index
  14. Half-life and the time required to reach steady state after a repeated administration
  15. Tolerance, tachyphylaxis
  16. Drug interactions
  17. Drug allergy, anaphylactic shock, bronchospasm, skin reactions
  18. Teratogenic effects of drugs
  19. Prescribing for the elderly, dosage in children
  20. Adverse drug reactions, serious ADRs, reporting ADRs
  21. Pre-clinical evaluation of new drugs
  22. Clinical evaluation of new drugs
  23. Therapeutic drug monitoring (TDM). Sources of drug information

Drug groups[edit | edit source]

  1. Antihypertensive agents
  2. Diuretics
  3. Beta-adrenergic antagonists (beta-blockers)
  4. Calcium channel blockers
  5. ACE inhibitors and angiotensin II inhibitors
  6. Centrally acting antihypertensive agents, alfa –adrenoceptor-blocking agents
  7. Drugs used to treat angina pectoris
  8. Nitrates
  9. Vasodilators
  10. Positive inotropic drugs and sympathomimetic drugs used in the treatment of cardiovasculars disorders
  11. Positive inotropic drugs
  12. drugs
  13. Antihistamines
  14. Ergot alkaloids
  15. Polypeptides
  16. Eicosanoids, prostaglandins
  17. Drugs used in asthma
  18. Bronchodilators
  19. Expectorants
  20. Anxiolytic
  21. Anxiolytic agents
  22. Benzodiazepines
  23. Sedative-hypnotics
  24. Ethanol
  25. Antiepileptic drugs
  26. General anesthetics
  27. Local anesthetics
  28. Skeletal muscle relaxants
  29. Drugs for Parkinson's disease
  30. Antipsychotic agents (neuroleptics)
  31.  Phenothiazines
  32. Lithium
  33.  Antidepressant agents
  34. Opioid analgesics & antagonists
  35. Nonopioid analgesics
  36.  Antimigraine drugs
  37.  Drugs of abuse
  38.  Agents used in anemias
  39.  Anticoagulant drugs & their antagonists
  40.  Fibrinolytic drugs, antiplatelet drugs
  41.  Agents used in hyperlipidemia . Plasma substitutes,
  42.  Non-steroidal antiinflamatory drugs
  43.  Drugs used in gout
  44.  Hypothalamic & pituitary hormones
  45.  Thyroid & antithyroid drugs
  46.  Corticosteroids
  47.  Gonadal hormones & inhibitors
  48.  Contraceptives
  49.  Pancreatic hormones & antidiabetic drugs
  50.  Drugs affecting bone metabolism
  51. Penicillins
  52.  Basic penicillins
  53.  Broad spectrum penicillins
  54.  Cephalosporins
  55.  Antibiotics against Staphylococcus
  56.  Tetracyclines
  57.  Aminoglycosides
  58.  Macrolides
  59.  Antimycobacterial drugs
  60.  Sulfonamides and trimethoprim
  61.  Antifungal agents
  62.  Chemotherapy of urinary tract infections
  63.  Treatment of trichomoniasis, Antimalarial agents
  64.  Antiviral agents
  65.  Antihelmintic drugs , ectoparasiticides
  66.  Cancer chemotherapy
  67.  Immunosuppressive and immunomodulating agents
  68.  Chelators
  69.  Drugs used in glaucoma therapy
  70.  Dermatologic agents
  71.  Drugs used in rhino- and laryngology
  72.  Drugs used in dermatology
  73.  Drugs used in the treatment for acne
  74.  Topical corticosteroids
  75.  Drugs used in gastrointestinal disease
  76.  Drugs used in acid-peptic disease
  77.  Antiemetics
  78.  Laxatives
  79.  Antidiarrheal agents
  80.  Spasmolytic agents and spasmoanalgesics
  81.  Vitamins
  82.  Disinfectants and antiseptics
  83.  Calcium, magnesium, potassium, sodium, Fluor
  84. Homeopathy
  85.  Drugs used in the obesity treatment
  86.  Uterotonics, tocolytic agents
  87. Specific antidotes used in management of the poisoned patient