Portal:Exam Topics in Biology and Medical Genetics (1. LF, D)

Exam Topic 1
- Genotype and its variability, mutation, recombination
- Genetic control of antibody production
- Prevention and early diagnostics of inherited diseases
Exam Topic 2
- Genotype and environment
- Mitosis, its regulation and defects
- The inheritance and biological importance of blood group systems
Exam Topic 3
- Methods of genetic analysis in experimental and human genetics
- Structure and reproduction of bacteria, importance for medicine
- The inheritance and biological importance of Rh system
Exam Topic 4
- Fundamental laws of genetics, Mendel´s experiments
- Cell cycle, its regulation and defects
- Human major histocompatibility complex
Exam Topic 5
- Genealogical method
- DNA structure and function
- Immunocompetent cells
Exam Topic 6
- Autosomal dominant inheritance in experiment and pedigrees, examples of human traits
- RNA types, structure and function
- Genetic control of immune response
Exam Topic 7
- Autosomal recessive inheritance in experiment and pedigrees, examples of human traits
- Gene structure and function
- Transplantation rules
Exam Topic 8
- Gonosomal inheritance in experiment and pedigrees, examples of human traits
- DNA replication
- Detection and prevention of inherited chromosomal aberrations
Exam Topic 9
- Multifactorial inheritance
- Genetic code
- Indication of chromosomal analysis
Exam Topic 10
- Human traits with multifactorial inheritance
- Protein-coding and non-coding DNA sequences
- Genetics of transplantations, transplantation rules, histocompatibility systems
Exam Topic 11
- Heritability and significance of its assessment in medicine
- Translation, post-translational protein modifications
- Syndromes of autosomal aneuploidies
Exam Topic 12
- Dihybridism, interaction of non-allelic genes, polyhybridism
- Transcription and post-transcriptional modifications of RNA in Eukaryotes
- Environmental mutagenic and teratogenic factors
Exam Topic 13
- Multiple alleles
- Genetics of aging and death
- Aims and mission of medical genetics
Exam topic 14
- Genetic linkage
- Regulation of gene function in Prokaryotes
- Preconception prevention of heritable diseases
Exam Topic 15
- Genetic methods of linkage analysis
- Gene mutation, types and manifestation
- Tumorigenesis, cancerogenesis, cancerogens
Exam Topic 16
- Crossing-over, its mechanism and importance
- Regulation of gene function in Eukaryotes
- Screening of heritable diseases
Exam Topic 17
- Molecular basis of heritable disease
- Somatic and gametic (germline) chromosomal aberrations
- Genetic counseling and its importance
Exam Topic 18
- Epigenetics, "thrifty" genotype and "thrifty" phenotype
- Mutagens a mutagenesis, testing of mutagenicity
- Characteristics of cancer development
Exam Topic 19
- Extrachromosomal inheritance, non-Mendelian inheritance
- Reparation mechanisms of nucleic acids
- Ethical and legal aspects of medical genetics
Exam Topic 20
- The importance and structure of Eukaryotic chromosomes
- The Inborn Errors of Metabolism
- Population genetics, C-H-W equilibrium
Exam Topic 21
- Population polymorphisms and their causes
- Methods of nucleic acids analysis
- Chromosomal aberrations in etiology of neoplasia
Exam Topic 22
- Inbreeding, consanguineous marriage and its risks
- Chromosome number and structure, techniques of examination
- Ontogenesis of sex in mammals and its defects
Exam Topic 23
- Prenatal diagnostics of inherited disease
- Transcription and post-transcriptional modifications of RNA in Prokaryotes
- Teratogenesis, teratogens
Exam Topic 24
- Small populations, genetic drift, importance for evolution
- Hemoglobinopathies
- Inherited diseases of development in man, examples, partition according to causes
Exam Topic 25
- Meiosis, its regulation and defects
- Conjugation, transformation, transduction
- Reparation mechanisms of the organism and their genetic control
Exam Topic 26
- Gametogenesis
- Direct and indirect diagnostics of heritable diseases by nucleic acid analysis
- Causes of chromosomal aberration
Exam Topic 27
- Genealogical methods
- The importance and structure of chromosomes of Prokaryotes
- Prenatal diagnostics of inherited disease
Exam Topic 28
- Human karyotype, methods of its examination
- Structure and function of Eukaryotic cell
- Characteristics of cancer cells
Exam Topic 29
- Aberrations of chromosome number, their causes and clinical presentation
- Cell signaling pathways
- Familial tumors
Exam Topic 30
- Syndromes of gonosome aneuploidies
- Tumor-supressor genes
- Structure and function of Prokaryotes
Exam Topic 31
- Aberrations affecting chromosome structure
- Protooncogenes, oncogenes
- Cultivation of cells and tissues in vitro, importance in medicine
Exam Topic 32
- Chromosomal sex determination
- Genetic regulation in multicellular organisms
- Prenatal screening of inherited disease