Congenic Strain

From WikiLectures

This article was checked by pedagogue
This article was checked by pedagogue  

This article was checked by pedagogue, but more than year ago.

Signature:  OSeda (talk)

Old checked article.png


English: congenic strain
Czech: kongenní kmen
Dictionary


Congenic strains are special type of strains where a specific and defined part of the genome from one inbred strain (strain A) is introgressed on the genetic background of second inbred strain (strain B). The congenic strain is an inbred strain, so it is homozygous throughout the whole genome, the only difference between strain B and congenic strain B.A# (where # is a specific number of the chromosome) is just the "differential" segment of chromosome #. If strain B and congenic strain B.A# differ in any phenotype (body weight, glycemia, or sensitivity to teratogen), it can be assumed that within the differential segment there is a gene or there are genes responsible for genetic determination of the studied phenotype. Special types of congenic strains include consomic strains and conplastic strains.

CONGENIC STRAIN.png

Links[edit | edit source]

Related articles[edit | edit source]

Bibliography[edit | edit source]