Regulation Mechanisms of Blood Flow in Organs

Contents 1 Overview 2 Specific needs of the organs for blood flow 3 Mechanisms of blood flow control 3.1 Short-tem control 3.2 Long-term control 4 Conclusion 5 Bibliography

edit Overview

In human body each organ has ability to control its own local blood flow in proportion to its metabolic needs. There are variations in blood flow in different organs like in brain, heart, kidneys, liver and etc. For example: the brain is responsible for receive and send messages from sensory organs to motor ones, for this he needs to have a good support from oxygen and nutrients.

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edit Specific needs of the organs for blood flow

The organs receive from blood O₂, nutrients; remove CO₂ and H⁺; maintenance of proper concentrations of other ions and transport of various hormones and other substances to the different tissues.

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edit Mechanisms of blood flow control

There are two phases of blood flow control short-term and long-term control. They differ among them for example in duration. In certain conditions one of the phases (e.g.short-term) can be switched on and if the organism's normal functioning is not restored, the other phase can then be activated, they compensate each other.

edit Short-tem control

• rapid changes in local vasodilation or vasoconstriction (arterioles, metarterioles, and precapillary sphincters)

• seconds to minutes

edit Long-term control

• result of a increase or decrease in the physical sizes and numbers of actual blood vessels

• over a period of days, weeks, or months

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edit Conclusion

To ensure the proper functioning of the organs they make their own control of nutrients, oxygen and removal of metabolic waste. This control is divided into two phases. The first has a shorter duration (short-term) and acts at the level of the capillary sphincters (vasodilation or vasoconstriction, depending on the situation), on the other hand the long-term has a longer duration and resulted in increased or decreased of blood vessels for a given organ. The lack of oxygen is received by receptors who send the message to the hypothalamus, the hypothalamus to the spinal cord and then to the heart and blood vessels.

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edit Bibliography

• Guyton & Hall Handbook

• http://www.apps.org.au/Proceedings/32-1/dampney/dampney.pdf

• http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1355131/pdf/annsurg00264-0082.pdf

• http://www.cvphysiology.com/Blood%20Flow/BF003.htm