Description of the Chromosome

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When we want to describe the location of some structural abnormality or the location os some specific region (e.g. gene locus) we use special marks. We have to count the regions always from the centromere – for both arms.

Example: 1q13

Chromosomal marking
  • the first number is the number of chromosomechromosome 1;
  • (p) and (q) are used for the marking of arm – (p) for small arm and (q) for long arm – the long arm;
  • the third number is for the region of chromosome – region 1;
  • last number is for the bandband 3.

So the change is located on the long arm of chromosome 1 (see Fig. Chromosomal marking).


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Bibliography

  • KUMAR, ABBAS, FAUSTO, MITCHELL,, et al. Robbins Basic Pathology. 8th edition edition. 2007. ISBN 978-0-8089-2366-4.